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Matured hiPSC-derived cardiomyocytes possess dematuration plasticity

Human induced Pluripotent Stem Cell-derived cardiomyocytes (hiPSC-CMs) are increasingly used to identify potential factors capable of inducing endogenous cardiomyocyte proliferation to regenerate the injured heart. L-type calcium channel blockers have previously been identified as a class of factors...

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Autores principales: Fang Meng, Maxwell Kwok, Yen Chin Hui, Ruofan Wei, Alejandro Hidalgo-Gonzalez, Anna Walentinsson, Henrik Andersson, Frederik Adam Bjerre, Qing-Dong Wang, Ditte C. Andersen, Ellen Ngar-Yun Poon, Daniela Später, David C. Zebrowski
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2025-06-01
Colección:Journal of Molecular and Cellular Cardiology Plus
Materias:
Cardiomyocyte
Stem cell
hiPSC
Proliferation
Differentiation
Maturation
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2772976125000145
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