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Upregulation of Mitochondrial Redox Sensitive Proteins in LPS-Treated Stefin B-Deficient Macrophages

Stefin B (cystatin B) is an intracellular inhibitor of cysteine cathepsins and mutations in the stefin B gene, resulting in the development of Unverricht−Lundborg disease, which is a form of myoclonic epilepsy. It was suggested that a key mechanism behind stefin B-mediated disease progression...

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Principais autores: Mojca Trstenjak Prebanda, Janja Završnik, Boris Turk, Nataša Kopitar Jerala
格式: Artigo
语言:Inglês
出版: MDPI AG 2019-11-01
丛编:Cells
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在线阅读:https://www.mdpi.com/2073-4409/8/12/1476
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