Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice

Cystatin C is a potent cysteine protease inhibitor that plays an important role in various biological processes including cancer, cardiovascular diseases and neurodegenerative diseases. However, the role of CstC in inflammation is still unclear. In this study we demonstrated that cystatin C-deficien...

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Hlavní autoři:	Monika Biasizzo, Mojca Trstenjak-Prebanda, Klemen Dolinar, Sergej Pirkmajer, Janja Završnik, Boris Turk, Nataša Kopitar-Jerala
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-08-01
Edice:	Cells
Témata:	Cystatin C lipopolysaccharide NLRP3 inflammasome autophagy cysteine proteases interleukin-1 (IL-1)
On-line přístup:	https://www.mdpi.com/2073-4409/10/8/2071
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