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Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses

Host cell-intrinsic antiviral responses are largely mediated by pattern-recognition receptor (PRR) signaling and the interferon (IFN) system. The IFN regulatory factor (IRF) family of transcription factors takes up a central role in transcriptional regulation of antiviral innate immunity. IRF3 and I...

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Principais autores: Sandra Wüst, Paulina Schad, Sandy Burkart, Marco Binder
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-09-01
coleção:Cells
Assuntos:
innate immunity
antiviral response
interferon
cytokines
RIG-I-like receptors
RLR signaling
Acesso em linha:https://www.mdpi.com/2073-4409/10/10/2600
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