IRF7 Is Required for the Second Phase Interferon Induction during Influenza Virus Infection in Human Lung Epithelia

Influenza A virus (IAV) infection is a major cause of morbidity and mortality. Retinoic acid-inducible protein I (RIG-I) plays an important role in the recognition of IAV in most cell types, and leads to the activation of interferon (IFN). We investigated mechanisms of RIG-I and IFN induction by IAV...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Wenxin Wu, Wei Zhang, Lili Tian, Brent R. Brown, Matthew S. Walters, Jordan P. Metcalf
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2020-03-01
Serija:	Viruses
Teme:	RIG-I IRF3 IRF7 TLR3 interferon influenza
Online dostop:	https://www.mdpi.com/1999-4915/12/4/377
Oznake:	Označite Brez oznak, prvi označite!