Imaging the TGFβ type I receptor in pulmonary arterial hypertension

Abstract Transforming growth factor β (TGFβ) activity is perturbed in remodelled pulmonary vasculature of patients with pulmonary arterial hypertension (PAH), cancer, vascular diseases and developmental disorders. Inhibition of TGFβ, which signals via activin receptor-like kinase 5 (ALK5), prevents...

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Principais autores:	Lonneke Rotteveel, Alex J. Poot, Esther J. M. Kooijman, Robert C. Schuit, Ingrid Schalij, Xiaoqing Sun, Kondababu Kurakula, Chris Happé, Wissam Beaino, Peter ten Dijke, Adriaan A. Lammertsma, Harm Jan Bogaard, Albert D. Windhorst
Format:	Artigo
Jezik:	Inglês
Izdano:	SpringerOpen 2023-03-01
Serija:	EJNMMI Research
Teme:	TGFβ type I receptor ALK5 Positron emission tomography Pulmonary arterial hypertension SuHx MCT
Online dostop:	https://doi.org/10.1186/s13550-023-00966-7
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