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Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract

Abstract Background Metabolic reprogramming is one of the hallmarks of cancer which favours rapid energy production, biosynthetic capabilities and therapy resistance. In our previous study, we showed bitter melon extract (BME) prevents carcinogen induced mouse oral cancer. RNA sequence analysis from...

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Autors principals: Subhayan Sur, Hiroshi Nakanishi, Colin Flaveny, Joseph E. Ippolito, Jane McHowat, David A. Ford, Ratna B. Ray
Format: Artigo
Idioma:Inglês
Publicat: BMC 2019-10-01
Col·lecció:Cell Communication and Signaling
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Accés en línia:http://link.springer.com/article/10.1186/s12964-019-0447-y
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