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Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract

Abstract Background Metabolic reprogramming is one of the hallmarks of cancer which favours rapid energy production, biosynthetic capabilities and therapy resistance. In our previous study, we showed bitter melon extract (BME) prevents carcinogen induced mouse oral cancer. RNA sequence analysis from...

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Autori principali: Subhayan Sur, Hiroshi Nakanishi, Colin Flaveny, Joseph E. Ippolito, Jane McHowat, David A. Ford, Ratna B. Ray
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2019-10-01
Serie:Cell Communication and Signaling
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Accesso online:http://link.springer.com/article/10.1186/s12964-019-0447-y
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