PLS-α-GalCer: a novel targeted glycolipid therapy for solid tumors

Background The prototypical type I natural killer T (NKT) cell agonist, α-galactosylceramide (α-GalCer), has shown only minimal effects against solid tumors in the clinic. The most promising clinical application of α-GalCer currently entails ex vivo priming of patient-derived dendritic cells; howeve...

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Hlavní autoři:	Jay A Berzofsky, Shweta Tiwary, Julian Burks, David M Stevens, Sarah L Skoczen, Ruvanthi N Kularatne, Stephan T Stern
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMJ Publishing Group 2025-03-01
Edice:	Journal for ImmunoTherapy of Cancer
On-line přístup:	https://jitc.bmj.com/content/13/3/e009539.full
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