Sustainable Protocol for the Synthesis of 2′,3′-Dideoxynucleoside and 2′,3′-Didehydro-2′,3′-dideoxynucleoside Derivatives

An improved protocol for the transformation of ribonucleosides into 2′,3′-dideoxynucleoside and 2′,3′-didehydro-2′,3′-dideoxynucleoside derivatives, including the anti-HIV drugs stavudine (d4T), zalcitabine (ddC) and didanosine (ddI), was established. The process involves radical deoxygenation of xa...

Descrición completa

Detalles Bibliográficos

Principais autores:	Virginia Martín-Nieves, Yogesh S. Sanghvi, Susana Fernández, Miguel Ferrero
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2022-06-01
Series:	Molecules
Assuntos:	2′,3′-dideoxynucleosides 2′,3′-didehydro-2′,3′-dideoxynucleosides synthesis zalcitabine (ddC) didanosine (ddI) stavudine (d4T)
Acceso en liña:	https://www.mdpi.com/1420-3049/27/13/3993
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!