The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function

Abstract PGC-1α plays a central role in maintaining mitochondrial and energy metabolism homeostasis, linking external stimuli to transcriptional co-activation of genes involved in adaptive and age-related pathways. The carboxyl-terminus encodes a serine/arginine-rich (RS) region and an RNA recogniti...

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Autors principals:	Simeon R. Mihaylov, Lydia M. Castelli, Ya-Hui Lin, Aytac Gül, Nikita Soni, Christopher Hastings, Helen R. Flynn, Oana Păun, Mark J. Dickman, Ambrosius P. Snijders, Robert Goldstone, Oliver Bandmann, Tatyana A. Shelkovnikova, Heather Mortiboys, Sila K. Ultanir, Guillaume M. Hautbergue
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2023-09-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-023-41304-8
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