Targeting Tristetraprolin Expression or Functional Activity Regulates Inflammatory Response Induced by MSU Crystals

The RNA-binding protein tristetraprolin (TTP) is an anti-inflammatory factor that prompts the mRNA decay of target mRNAs and is involved in inflammatory diseases such as rheumatoid arthritis (RA). TTP is regulated by phosphorylation, and protein phosphatase 2A (PP2A) can dephosphorylate TTP to activ...

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Главные авторы:	Linxi lv, Ting Qin, Qiushi Huang, Hui Jiang, Feng Chen, Fan Long, Long Ren, Jianpin Liu, Yongen Xie, Mei Zeng
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2021-07-01
Серии:	Frontiers in Immunology
Предметы:	TTP Arctigenin NLRP3 inflammasome mitochondrial ROS autophagic flux 3
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.675534/full
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