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Glutathione Transferases as Efficient Ketosteroid Isomerases

In addition to their well-established role in detoxication, glutathione transferases (GSTs) have other biological functions. We are focusing on the ketosteroid isomerase activity, which appears to contribute to steroid hormone biosynthesis in mammalian tissues. A highly efficient GST A3-3 is present...

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Principais autores: Bengt Mannervik, Aram Ismail, Helena Lindström, Birgitta Sjödin, Nancy H. Ing
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-11-01
Serier:Frontiers in Molecular Biosciences
Fag:
ketosteroid isomerase
androstenedione
progesterone
ecdysteroid
glutathione
steroid hormone
Online adgang:https://www.frontiersin.org/articles/10.3389/fmolb.2021.765970/full
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