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Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity

The spread of Human Immunodeficiency Virus (HIV) still represents a global public health issue of major concern, and would benefit from unveiling unique viral features as targets for drug design. In this respect, HIV-1 integrase (IN), due to the absence of homologs in human cells, is a popular targe...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Graziella Tocco, Serena Canton, Antonio Laus, Pierluigi Caboni, Stuart F. J. Le Grice, Enzo Tramontano, Francesca Esposito
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2023-09-01
Rangatū:Molecules
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1420-3049/28/18/6700
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