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OLFM4 modulates intestinal inflammation by promoting IL-22+ILC3 in the gut

Abstract Group 3 innate lymphoid cells (ILC3s) play key roles in intestinal inflammation. Olfactomedin 4 (OLFM4) is highly expressed in the colon and has a potential role in dextran sodium sulfate-induced colitis. However, the detailed mechanisms underlying the effects of OLFM4 on ILC3-mediated coli...

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主要な著者: Zhe Xing, Xinyao Li, Junyu He, Yimin Chen, Lei Zhu, Xiaogang Zhang, Zhengcong Huang, Jian Tang, Yuxiong Guo, Yumei He
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2024-07-01
シリーズ:Communications Biology
オンライン・アクセス:https://doi.org/10.1038/s42003-024-06601-y
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