Characterization of PROTAC specificity and endogenous protein interactomes using ProtacID
Abstract Here we describe ProtacID, a flexible BioID (proximity-dependent biotinylation)-based approach to identify PROTAC-proximal proteins in living cells. ProtacID analysis of VHL- and CRBN-recruiting PROTACs targeting a number of different proteins (localized to chromatin or cellular membranes,...
Gorde:
| Egile Nagusiak: | , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Portfolio
2025-08-01
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| Saila: | Nature Communications |
| Sarrera elektronikoa: | https://doi.org/10.1038/s41467-025-63357-7 |
| Etiketak: |
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