Characterization of PROTAC specificity and endogenous protein interactomes using ProtacID
Abstract Here we describe ProtacID, a flexible BioID (proximity-dependent biotinylation)-based approach to identify PROTAC-proximal proteins in living cells. ProtacID analysis of VHL- and CRBN-recruiting PROTACs targeting a number of different proteins (localized to chromatin or cellular membranes,...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Portfolio
2025-08-01
|
| Collection: | Nature Communications |
| Accès en ligne: | https://doi.org/10.1038/s41467-025-63357-7 |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|