The multifaceted role of PUMA in cell death pathways: its therapeutic potential across cancer types

Abstract Cell death is a fundamental process essential to all living organisms, with apoptosis serving as one of the most crucial pathways across various stages of life. Dysregulation of apoptosis is closely associated with numerous diseases, particularly cancer. PUMA (p53 upregulated modulator of a...

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Autors principals:	Sharad Shriram Tat, Kartik Mandal, Tanisha Sharma, Nikhil Baban Ghate, Ganesh Kumar Barik, Rajesh N. Gachhe, Manas Kumar Santra
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-11-01
Col·lecció:	Cell Communication and Signaling
Matèries:	PUMA Apoptosis Drug resistance Autophagy Necroptosis Ferroptosis
Accés en línia:	https://doi.org/10.1186/s12964-025-02112-3
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