Combined transfection of Bcl-2 siRNA and miR-15a oligonucleotides enhanced methotrexate-induced apoptosis in Raji cells

<b>Objective:</b>B-cell lymphoma 2 (Bcl-2) is an important member of the Bcl-2 family of proteins that regulate the induction of apoptosis. This study aims to investigate whether Bcl-2 small interfering RNA (siRNA) combined with miR-15a oligonucleotides (ODN) could enhance methotrexate (MTX)-induced...

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Hlavní autoři:	Li Ding, Xiao-Mao Hu, Hong Wu, Ge-Xiu Liu, Yang-Jun Gao, Dong-Mei He, Yuan Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	China Anti-Cancer Association 2013-03-01
Edice:	Cancer Biology & Medicine
Témata:	B-cell lymphoma 2 (Bcl-2) small interfering RNA oligonucleotide methotrexate Raji cell miR-15a apoptosis
On-line přístup:	http://www.cancerbiomed.org/index.php/cocr/article/view/586
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