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Combined transfection of Bcl-2 siRNA and miR-15a oligonucleotides enhanced methotrexate-induced apoptosis in Raji cells

<b>Objective:</b>B-cell lymphoma 2 (Bcl-2) is an important member of the Bcl-2 family of proteins that regulate the induction of apoptosis. This study aims to investigate whether Bcl-2 small interfering RNA (siRNA) combined with miR-15a oligonucleotides (ODN) could enhance methotrexate (MTX)-induced...

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Principais autores: Li Ding, Xiao-Mao Hu, Hong Wu, Ge-Xiu Liu, Yang-Jun Gao, Dong-Mei He, Yuan Zhang
Formato: Artigo
Idioma:Inglês
Publicado: China Anti-Cancer Association 2013-03-01
Series:Cancer Biology & Medicine
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Acceso en liña:http://www.cancerbiomed.org/index.php/cocr/article/view/586
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