GPX4 alleviates airway inflammation by suppressing 5-LO expression and regulating ferroptosis
Abstract Ferroptosis has been increasingly implicated in the pathophysiology of asthma. Glutathione peroxidase 4 (GPX4), the key enzymatic suppressor of ferroptosis, has a role in asthma that remains insufficiently defined. Here, we investigated the regulatory function of GPX4 in asthma airway epith...
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| Principais autores: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BMC
2026-02-01
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| 叢編: | Respiratory Research |
| 主題: | |
| 在線閱讀: | https://doi.org/10.1186/s12931-026-03584-8 |
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