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Polygenic risk scores: the future of cancer risk prediction, screening, and precision prevention

Genome-wide association studies (GWASs) have shown that the genetic architecture of cancers are highly polygenic and enabled researchers to identify genetic risk loci for cancers. The genetic variants associated with a cancer can be combined into a polygenic risk score (PRS), which captures part of...

詳細記述

保存先:
書誌詳細
主要な著者: Wang Yuzhuo, Zhu Meng, Ma Hongxia, Shen Hongbing
フォーマット: Artigo
言語:Inglês
出版事項: De Gruyter 2021-12-01
シリーズ:Medical Review
主題:
オンライン・アクセス:https://doi.org/10.1515/mr-2021-0025
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