Polygenic risk scores: the future of cancer risk prediction, screening, and precision prevention
Genome-wide association studies (GWASs) have shown that the genetic architecture of cancers are highly polygenic and enabled researchers to identify genetic risk loci for cancers. The genetic variants associated with a cancer can be combined into a polygenic risk score (PRS), which captures part of...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
De Gruyter
2021-12-01
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| Col·lecció: | Medical Review |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1515/mr-2021-0025 |
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