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Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G.

Protease-mediated degradation of proteins is critical in a plethora of physiological processes. Neutrophils secrete serine proteases including cathepsin G (CatG), neutrophile elastase (NE), and proteinase 3 (PR3) together with lactoferrin (LF) as a first cellular immune response against pathogens. H...

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Principais autores: Steffen Eipper, Robin Steiner, Adam Lesner, Marcin Sienczyk, David Palesch, Marc-Eric Halatsch, Ewa Zaczynska, Christopher Heim, Marcus D Hartmann, Michal Zimecki, Christian Rainer Wirtz, Timo Burster
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2016-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4795699?pdf=render
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