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Obesity Prolongs the Inflammatory Response in Mice After Severe Trauma and Attenuates the Splenic Response to the Inflammatory Reflex

Thoracic traumas with extra-thoracic injuries result in an immediate, complex host response. The immune response requires tight regulation and can be influenced by additional risk factors such as obesity, which is considered a state of chronic inflammation. Utilizing high-dimensional mass and regula...

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Principais autores: Fabian Gärtner, Adrian Gihring, Aileen Roth, Joachim Bischof, Pengfei Xu, Leonard Elad, Martin Wabitsch, Timo Burster, Uwe Knippschild
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-11-01
Serier:Frontiers in Immunology
Fag:
obesity
immune response
severe trauma
inflammatory reflex
monocyte compartment
mass cytometry (CyTOF)
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2021.745132/full
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