Precision screening facilitates clinical classification of BRCA2-PALB2 binding variants with benign and pathogenic functional effects
BACKGROUND Decoding the clinical impact of genetic variants is particularly important for precision medicine in cancer. Genetic screening of mainly patients with breast and ovarian cancer has identified numerous BRCA1/BRCA2 variants of uncertain significance (VUS) that remain unclassified owing to a...
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
American Society for Clinical Investigation
2025-06-01
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| Цуврал: | The Journal of Clinical Investigation |
| Нөхцлүүд: | |
| Онлайн хандалт: | https://doi.org/10.1172/JCI181879 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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