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Chimeric antigen receptors discriminate between tau and distinct amyloid-beta species

Abstract Background The lack of a definitive cure for Alzheimer's disease (AD) is fueling the search for innovative therapeutic strategies. Having revolutionized cancer immunotherapy, immune cell engineering with chimeric antigen receptors (CAR) is being explored to target AD. Whether CARs can recog...

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Autors principals: Cynthia J. Siebrand, Nicholas J. Bergo, Suckwon Lee, Julie K. Andersen, Chaska C. Walton
Format: Artigo
Idioma:Inglês
Publicat: BMC 2025-05-01
Col·lecció:Journal of Translational Medicine
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Accés en línia:https://doi.org/10.1186/s12967-025-06572-6
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