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Chimeric antigen receptors discriminate between tau and distinct amyloid-beta species

Abstract Background The lack of a definitive cure for Alzheimer's disease (AD) is fueling the search for innovative therapeutic strategies. Having revolutionized cancer immunotherapy, immune cell engineering with chimeric antigen receptors (CAR) is being explored to target AD. Whether CARs can recog...

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Principais autores: Cynthia J. Siebrand, Nicholas J. Bergo, Suckwon Lee, Julie K. Andersen, Chaska C. Walton
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2025-05-01
Series:Journal of Translational Medicine
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Acceso en liña:https://doi.org/10.1186/s12967-025-06572-6
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