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Prolonged dialysis during ex vivo lung perfusion promotes inflammatory responses

Ex-vivo lung perfusion (EVLP) has extended the number of transplantable lungs by reconditioning marginal organs. However, EVLP is performed at 37°C without homeostatic regulation leading to metabolic wastes’ accumulation in the perfusate and, as a corrective measure, the costly perfusate is repeated...

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Hoofdauteurs: Julien De Wolf, Carla Gouin, Luc Jouneau, Matthieu Glorion, Antoine Premachandra, Florentina Pascale, Maxime Huriet, Jérôme Estephan, Jean-Jacques Leplat, Giorgia Egidy, Christophe Richard, Valérie Gelin, Céline Urien, Antoine Roux, Morgan Le Guen, Isabelle Schwartz-Cornil, Edouard Sage
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2024-03-01
Reeks:Frontiers in Immunology
Onderwerpen:
lung
transplantation
ex vivo
ischemia-reperfusion
dialysis
ex vivo lung perfusion
Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1365964/full
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