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Prolonged dialysis during ex vivo lung perfusion promotes inflammatory responses

Ex-vivo lung perfusion (EVLP) has extended the number of transplantable lungs by reconditioning marginal organs. However, EVLP is performed at 37°C without homeostatic regulation leading to metabolic wastes’ accumulation in the perfusate and, as a corrective measure, the costly perfusate is repeated...

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Guardat en:
Autors principals: Julien De Wolf, Carla Gouin, Luc Jouneau, Matthieu Glorion, Antoine Premachandra, Florentina Pascale, Maxime Huriet, Jérôme Estephan, Jean-Jacques Leplat, Giorgia Egidy, Christophe Richard, Valérie Gelin, Céline Urien, Antoine Roux, Morgan Le Guen, Isabelle Schwartz-Cornil, Edouard Sage
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-03-01
Col·lecció:Frontiers in Immunology
Matèries:
lung
transplantation
ex vivo
ischemia-reperfusion
dialysis
ex vivo lung perfusion
Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1365964/full
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