QR kód

Methylmalonic acidemia triggers lysosomal-autophagy dysfunctions

Abstract Background Methylmalonic acidemia (MMA) is a rare inborn error of propionate metabolism caused by deficiency of the mitochondrial methylmalonyl-CoA mutase (MUT) enzyme. As matter of fact, MMA patients manifest impairment of the primary metabolic network with profound damages that involve se...

Celý popis

Uloženo v:
Hlavní autoři: Michele Costanzo, Armando Cevenini, Laxmikanth Kollipara, Marianna Caterino, Sabrina Bianco, Francesca Pirozzi, Gianluca Scerra, Massimo D’Agostino, Luigi Michele Pavone, Albert Sickmann, Margherita Ruoppolo
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-05-01
Edice:Cell & Bioscience
Témata:
Methylmalonic acidemia
Lysosomes
Autophagy
Metabolic disease
Multi-omics
Multi-proteomics
On-line přístup:https://doi.org/10.1186/s13578-024-01245-1
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Podobné jednotky