Exercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35/NFκB p65 pathway

Background: Reduced serum estrogen levels in postmenopausal patients not only aggravate bone loss but also impact myokine secretion. Emerging evidence has revealed the importance of myokines in bone metabolism, and exercise can interfere with the secretion of myokines. However, few studies have expl...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Tianshu Shi, Yong Shi, Hongliang Gao, Yuze Ma, Qianjin Wang, Siyu Shen, Xiaoyan Shao, Wang Gong, Xiang Chen, Jian Qin, Jing Wu, Qing Jiang, Bin Xue
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2022-07-01
Schriftenreihe:	Journal of Orthopaedic Translation
Schlagworte:	Postmenopausal osteoporosis Muscle–bone axis Kynurenic acid Exercise
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2214031X22000237
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!