Betulin Alleviates the Inflammatory Response in Mouse Chondrocytes and Ameliorates Osteoarthritis via AKT/Nrf2/HO-1/NF-κB Axis

Osteoarthritis (OA) is a common degenerative joint disease featuring the degeneration, destruction, and ossification of cartilage. Inflammation which may facilitate OA occurrence and development is considered as the main pathological factor. Betulin, a natural product extracted from birch bark, has...

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Detalhes bibliográficos

Principais autores:	Chenghao Ren, Jie Jin, Wei Hu, Qi Chen, Jian Yang, Yaosen Wu, Yifei Zhou, Liaojun Sun, Weiyang Gao, Xiaolei Zhang, Naifeng Tian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-10-01
coleção:	Frontiers in Pharmacology
Assuntos:	betulin osteoarthritis (OA) AKT NRF NF-κB inflammation
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2021.754038/full
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