An immunomodulatory photosensitizer-mediated photodynamic therapy synergizes with PD-L1 blockade against metastatic triple-negative breast cancer

The clinical potency of anti-programmed death-ligand 1 (PD-L1) therapy in metastatic triple-negative breast cancer (TNBC) is modest primarily because of the intrinsic low immunogenicity and an immunosuppressive tumor microenvironment (TME). Photodynamic therapy (PDT), an inducer of immunogenic cell...

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מידע ביבליוגרפי
Main Authors: Yuetong Liu, Liming Wang, Feiyan Kong, Tianjun Liu, Hong Liu
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2025-07-01
סדרה:Frontiers in Pharmacology
נושאים:
photodynamic therapy
immunogenic cell death
metastatic triple-negative breast cancer
programmed death-ligand 1 blockade
abscopal effect
systemic antitumor immunity
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fphar.2025.1651165/full
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