Preparation and physicochemical characterization of prazosin conjugated PLGA nanoparticles for drug delivery of flutamide
In the current work, a sustained drug delivery system of flutamide (FLT) was developed using Poly(D,L-lactide-co-glycolide) (PLGA) decorated bypoly(ethylene glycol) (PEG) grafted prazosin (PLGA-PEG-Praz) as a targeting moiety. In a multi-step reaction, PLGA was linked to PEG and prazosin. The struct...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
2019-04-01
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| シリーズ: | Brazilian Journal of Pharmaceutical Sciences |
| 主題: | |
| オンライン･アクセス: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000400609&lng=en&tlng=en |
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