Stealth Amphotericin B nanoparticles for oral drug delivery: In vitro optimization
Abstract Purpose Amphotericin B (AmB) is an effective anti-fungal and anti-leishmanial agent. However, AmB has low oral bioavailability (0.3%) and adverse effects (e.g., nephrotoxicity). The objectives of this study were to improve the oral bioavailability by entrapping AmB in pegylated (PEG) poly l...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer
2014-11-01
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| coleção: | Saudi Pharmaceutical Journal |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1016/j.jsps.2014.11.004 |
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