QR-koodi

A gp41 HR2 residue modulates the susceptibility of HIV-1 envelope glycoproteins to small molecule inhibitors targeting gp120

ABSTRACT One characteristic of the HIV-1 CRF01_AE strain is that it contains a bulkier histidine residue at position 375 (H375) in its envelope glycoproteins (Env). This residue is part of the Phe43 cavity, where residue 43 of CD4 engages with gp120. It has been shown that H375 contributes to resist...

Täydet tiedot

Tallennettuna:
Päätekijät: Debashree Chatterjee, Ling Niu, Halima Medjahed, Shilei Ding, Mehdi Benlarbi, Étienne Bélanger, Jérémie Prévost, Hung-Ching Chen, William D. Tolbert, Amos B. Smith, Marzena Pazgier, Andrés Finzi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2025-04-01
Sarja:Journal of Virology
Aiheet:
HIV
Env
gp120
gp41
CRF01_AE
temsavir
Linkit:https://journals.asm.org/doi/10.1128/jvi.02267-24
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia