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Increased frequencies of CD8+CD57+ T cells are associated with antibody neutralization breadth against HIV in viraemic controllers

Introduction An effective prophylactic vaccine against HIV will need to elicit antibody responses capable of recognizing and neutralizing rapidly evolving antigenic regions. The immunologic milieu associated with development of neutralizing antibody breadth remains to be fully defined. In this study...

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Principais autores: Christine D Palmer, Marisol Romero‐Tejeda, Eileen P Scully, Ainsley Lockhart, Michael S Seaman, Ariel Goldenthal, Alicja Piechocka‐Trocha, Bruce D Walker, Lori B Chibnik, Stephanie Jost, Filippos Porichis
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2016-01-01
coleção:Journal of the International AIDS Society
Assuntos:
HIV
broadly neutralizing antibody
T cells
immune monitoring
biomarker
immune signature
Acesso em linha:https://doi.org/10.7448/IAS.19.1.21136
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