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Associations Between Antibody Fc-Mediated Effector Functions and Long-Term Sequelae in Ebola Virus Survivors

Antibodies that mediate non-neutralizing functions play an important role in the immune response to Ebola virus (EBOV) and are thought to impact disease outcome. EBOV has also been associated with long term sequelae in survivors, however, the extent to which antibodies that mediate non-neutralizing...

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Autori principali: Dominic Paquin-Proulx, Bronwyn M. Gunn, Aljawharah Alrubayyi, Danielle V. Clark, Matthew Creegan, Dohoon Kim, Hannah Kibuuka, Monica Millard, Salim Wakabi, Leigh Anne Eller, Nelson L. Michael, Randal J. Schoepp, Matthew J. Hepburn, Lisa E. Hensley, Merlin L. Robb, Galit Alter, Michael A. Eller
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021-05-01
Serie:Frontiers in Immunology
Soggetti:
antibodies
Ebola
Fc-mediated antibody functions
inflammation
long term sequelae
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2021.682120/full
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