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Prognostic Importance of C-KIT Mutations in Core Binding Factor Acute Myeloid Leukemia: A Systematic Review

Objective/background: Acute myeloid leukemia (AML) is defined as leukemic blast reproduction in bone marrow. Chromosomal abnormalities form different subgroups with joint clinical specifications and results. t(8;21)(q22;q22) and inv(16)(p13;q22) form core binding factor- AML (CBF-AML). c-kit mutatio...

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Main Authors: Hossein Ayatollahi, Arezoo Shajiei, Mohammad Hadi Sadeghian, Maryam Sheikhi, Ehsan Yazdandoust, Masumeh Ghazanfarpour, Seyyede Fatemeh Shams, Sepideh Shakeri
Format: Artigo
Language:Inglês
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Hematology/Oncology and Stem Cell Therapy
Subjects:
cbf-aml
c-kit
t(821)
inv(16)
Online Access:https://journals.lww.com/10.1016/j.hemonc.2016.08.005
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