Co-differentiation and enrichment of corneal endothelial cells and keratocytes from human pluripotent stem cells

Abstract Corneal keratocytes (CK) and endothelial cells (CEnC) maintain corneal stromal transparency. Damage to these cell types can lead to visual impairment. Although corneal transplantation is effective, donor shortages limit its availability. Human pluripotent stem cells (hPSC) offer a promising...

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Detalhes bibliográficos

Principais autores:	Abhinav Reddy Kethiri, Pyry Grönroos, Ajai Suwaraj Chinnaiah Nagaraj, Heli Skottman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-05-01
coleção:	Scientific Reports
Assuntos:	Cornea Stroma Keratocytes Endothelium Pluripotent stem cell Differentiation
Acesso em linha:	https://doi.org/10.1038/s41598-025-03509-3
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