Crucial role of dendritic cells in the generation of anti-tumor T-cell responses and immunogenic tumor microenvironment to suppress tumor development

Dendritic cells (DCs) are known as unique professional antigen (Ag)-presenting cells (APCs) to prime naïve T cells for the initiation of adaptive immunity. While DCs are believed to play a pivotal role in generating anti-tumor T-cell responses, the importance of DCs in the protection from the progre...

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Bibliografische Detailangaben

Hauptverfasser:	Moe Tominaga, Tomofumi Uto, Tomohiro Fukaya, Shuya Mitoma, Dieter Riethmacher, Kunihiko Umekita, Yoshihiro Yamashita, Katsuaki Sato
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-08-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	dendritic cells tumor development anti-tumor T-cell responses tumor microenvironment myeloid-derived suppressor cells immunosuppressive mediators
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1200461/full
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