Congenital Deficiency of Conventional Dendritic Cells Promotes the Development of Atopic Dermatitis-Like Inflammation

Atopic dermatitis (AD) is a common pruritic inflammatory skin disease characterized by impaired epidermal barrier function and dysregulation of Thelper-2 (TH2)-biased immune responses. While the lineage of conventional dendritic cells (cDCs) are implicated to play decisive roles in T-cell immune res...

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Autori principali:	Yotaro Nishikawa, Tomohiro Fukaya, Takehito Fukui, Tomofumi Uto, Hideaki Takagi, Junta Nasu, Noriaki Miyanaga, Dieter Riethmacher, Narantsog Choijookhuu, Yoshitaka Hishikawa, Masahiro Amano, Katsuaki Sato
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-07-01
Serie:	Frontiers in Immunology
Soggetti:	atopic dermatitis dendritic cells type 2 immune responses immune homeostasis homeostatic feedback loop
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.712676/full
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