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Optimisation by Design of Experiment of Benzimidazol-2-One Synthesis under Flow Conditions

A novel flow-based approach for the preparation of benzimidazol-2-one (<b>1</b>) scaffold by the 1,1&#8242;-carbonyldiimidazole (CDI)-promoted cyclocarbonylation of <i>o</i>-phenylenediamine (<b>2</b>) is reported. Starting from a preliminary batch screening, the model reaction was successfully tran...

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Bibliografiske detaljer
Principais autores: Serena Mostarda, Tugçe Gür Maz, Alessandro Piccinno, Bruno Cerra, Erden Banoglu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-07-01
Serier:Molecules
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Online adgang:https://www.mdpi.com/1420-3049/24/13/2447
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