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PKC-δ mediates interferon-α-induced apoptosis through c-Jun NH<sub>2</sub>-terminal kinase activation

<p>Abstract</p> <p>Background</p> <p>Interferon-α (IFN-α) exerts an anti-tumor effect at least through induction of apoptosis in a variety of types including B lymphoma cells. We recently found that IFN-α induced a sustained activation of c-Jun NH<sub>2</sub>-terminal kinase1 (JNK1), which is implic...

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Autori principali: Yanase Noriko, Hayashida Miho, Kanetaka-Naka Yuki, Hoshika Akinori, Mizuguchi Junichiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-03-01
Serie:BMC Cell Biology
Soggetti:
Interferon-α
PKC-δ
JNKs
Apoptosis
B lymphoma cells
Accesso online:http://www.biomedcentral.com/1471-2121/13/7
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