Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson’s Disease

Oxidative stress, neuroinflammation and apoptosis are some of the key etiological factors responsible for dopamin(DA)ergic degeneration during Parkinson’s disease (PD), yet the downstream molecular mechanisms underlying neurodegeneration are largely unknown. Recently, a genome-wide association study...

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Главные авторы:	Hariharan Saminathan, Anamitra Ghosh, Danhui Zhang, Chunjuan Song, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2021-04-01
Серии:	Frontiers in Pharmacology
Предметы:	Fyn PKCδ neurodegeneration phosphorylation kinase
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fphar.2021.631375/full
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