Acetyl-CoA Metabolism and Histone Acetylation in the Regulation of Aging and Lifespan
Acetyl-CoA is a metabolite at the crossroads of central metabolism and the substrate of histone acetyltransferases regulating gene expression. In many tissues fasting or lifespan extending calorie restriction (CR) decreases glucose-derived metabolic flux through ATP-citrate lyase (ACLY) to reduce cy...
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| 主要作者: | |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI AG
2021-04-01
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| 叢編: | Antioxidants |
| 主題: | |
| 在線閱讀: | https://www.mdpi.com/2076-3921/10/4/572 |
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