Developing blood extracellular vesicle protein biomarkers for hepatocellular carcinoma: mechanisms, methods, and translation

Abstract Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality globally, with late-stage diagnoses predominantly driven by the absence of early clinical symptoms and the inadequate sensitivity of current diagnostic tools, highlighting a critical unmet need in liver cance...

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Hauptverfasser:	Yijia Zhuang, Wenjuan Zeng, Tingting Long, Nan Gao, Weitao Zhong, Hongyu Mu, Xinyuan Wang, Hao Yang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-04-01
Schriftenreihe:	Journal of Nanobiotechnology
Schlagworte:	Hepatocellular carcinoma Extracellular vesicles Proteomics Protein biomarkers Liquid biopsy
Online-Zugang:	https://doi.org/10.1186/s12951-026-04463-6
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