Combined Bisoprolol and Megestrol Acetate Improves Survival and Preserves Cardiac Performance in a Rat Model of Cancer Cachexia

ABSTRACT Background Cancer cachexia is associated with rapid body wasting and cardiac dysfunction. Bisoprolol (BIS) and megestrol acetate (MA) improve selected cachexia phenotypes in the Yoshida AH‐130 model, but their combined effects are not defined. We tested reduced‐dose combined treatment of BI...

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Váldodahkkit:	Zihao Chen, Siqi Wang, Sandra Palus, Stefan D. Anker, Wolfram Doehner, Jochen Springer
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Wiley 2026-06-01
Ráidu:	Journal of Cachexia, Sarcopenia and Muscle
Fáttát:	body composition body weight cancer cachexia cardiac function heart survival
Liŋkkat:	https://doi.org/10.1002/jcsm.70313
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