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Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer

<p>Abstract</p> <p>Hsulf-1 is a newly identified enzyme, which has the ability to decrease the growth of hepatocellular, ovarian, and head and neck squamous cell carcinoma cells by interfering with heparin-binding growth factor signaling. Since pancreatic cancers over-express a number of heparin-bin...

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Principais autores: Giese Nathalia A, Kayed Hany, Abiatari Ivane, Kleeff Jörg, Li Junsheng, Felix Klaus, Giese Thomas, Büchler Markus W, Friess Helmut
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2005-04-01
Serier:Molecular Cancer
Fag:
pancreatic cancer
growth factors
sulfatase
proteoglycans
Online adgang:http://www.molecular-cancer.com/content/4/1/14
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