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Myeloid-derived suppressor cell-derived osteoclasts with bone resorption capacity in the joints of arthritic SKG mice

BackgroundMyeloid-derived suppressor cells (MDSCs) are heterogeneous immature myeloid cells with immunosuppressive functions. It is known that MDSCs are expanded at inflammatory sites after migrating from bone marrow (BM) or spleen (Sp). In chronic inflammatory diseases such as rheumatoid arthritis...

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Hlavní autoři: Yoshikazu Fujikawa, Sho Sendo, Alfonso del Peral Fanjul, Hirotaka Yamada, Kenichi Uto, Yuzuru Yamamoto, Takumi Nagamoto, Akio Morinobu, Jun Saegusa
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-03-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1168323/full
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